Miwon launches DermaPep™ A530, a new pentapeptide designed for anti-inflammatory and antiaging skin care products. DermaPep™ A530 as a substance P antagonist effectively suppresses the production of UV-induced proinflammatory cytokines.
In vitro studies performed on human keratinocytes showed that DermaPep™ A530 powerfully inhibits the UV-stimulated expression and production of various proinflammatory cytokines such as IL-1α,IL-1β, IL-6, IL-8 and PGES.
DermaPep™ A530 is an ideal active to incorporate in cosmetic formulations designed not only to reduce key proinflammatory cytokine productions but also to suppress the production of the matrix metalloproteinase-1, an enzyme known to break down the interstitial collagens.
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